Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2008-09-08
2011-11-22
Kumar, Shailendra (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C546S336000, C514S357000, C514S619000
Reexamination Certificate
active
08063247
ABSTRACT:
Compounds of formula (I) or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful inter alia for the treatment of obesity.
REFERENCES:
patent: 6028175 (2000-02-01), Grandy et al.
patent: 6225080 (2001-05-01), Uhl et al.
patent: 2006/0217372 (2006-09-01), Blanco-Pillado et al.
patent: 2010/0113512 (2010-05-01), Ignar
patent: 2010/0173886 (2010-07-01), Bloxham et al.
patent: 0843726 (1998-05-01), None
patent: WO-9507983 (1995-03-01), None
patent: WO-9707212 (1997-02-01), None
patent: WO-03101963 (2003-12-01), None
patent: 2004026305 (2004-04-01), None
patent: WO-2004080968 (2004-09-01), None
patent: WO-2004080996 (2004-09-01), None
patent: WO-2005061442 (2005-07-01), None
patent: WO-2005066164 (2005-07-01), None
patent: WO-2005090286 (2005-09-01), None
patent: WO-2005090303 (2005-09-01), None
patent: WO-2005090337 (2005-09-01), None
patent: WO-2005092836 (2005-10-01), None
patent: WO-2007047397 (2007-04-01), None
patent: 2008021849 (2008-02-01), None
patent: WO-2008021851 (2008-02-01), None
patent: WO-2008032156 (2008-03-01), None
patent: 2008059335 (2008-05-01), None
International Search Report in PCT/GB2008/050801.
International Preliminary Report on Patentability and Written Opinion of the International Searching Authority in PCT/GB2008/050801.
Diaz et al., “SAR and biological evaluation of noveltrans-3,4-dimethyl-4-arylpiperidine derivatives as opioid antagonists.”Bioorg. Med. Chem. Lett., 15:3844-3848 (2005).
Takeuchi et al., “Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 2”,Bioorg. Med. Chem. Lett., 17:6841-6846 (2007).
Takeuchi et al., “Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part I”,Bioorg. Med. Chem. Lett., 17:5349-5352 (2007).
Zhang et al., “The μ-opioid receptor subtype is required for the anorectic effect of an opioid receptor antagonist”,Eur. J. Pharmacol., 545:147-152 (2006).
Bloxham Jason
Bradley Stuart Edward
Krulle Thomas Martin
Procter Martin James
Sambrook-Smith Colin Peter
Elrifi Ivor R.
Kumar Shailendra
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
Prosidion Limited
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