Bicyclic and tricyclic amines as modulators of chemokine...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S427000

Reexamination Certificate

active

07550500

ABSTRACT:
The present application describes modulators of CCR3 of formula (I):in-line-formulae description="In-line Formulae" end="lead"?A—E—NR1—G  (I)in-line-formulae description="In-line Formulae" end="tail"?or pharmaceutically acceptable salt forms thereof, useful for the prevention of inflammatory diseases such as asthma and other allergic diseases.

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Horuk and Ng, “Chemokine Receptor Antagonists”,Med. Res. Rev., vol. 20, pp. 155-168, 1999.

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