Bicyclic amine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

546112, A61K 31435, C07D47108

Patent

active

060937262

ABSTRACT:
A compound of formula (I): ##STR1## wherein Ar is optionally substituted phenyl or optionally substituted 5-or 6-membered heterocyclic ring containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, said heterocyclic ring being optionally fused to a benzene ring; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom, an insecticidal, acaricidal or nematicidal composition comprising a compound of formula (I) and a suitable carrier or diluent therefor, a method of combating and controlling insect, acarine or nematode pests at a locus which comprises treating the pests or the locus of the pests with an effective amount of a compound of formula (I) or a composition as hereinbefore described.

REFERENCES:
patent: 3120537 (1964-02-01), Archer et al.
patent: 3133073 (1964-05-01), Archer
patent: 3308131 (1967-03-01), McKusick
patent: 3501461 (1970-03-01), Newallis et al.
patent: 3546232 (1970-12-01), Kaiser et al.
patent: 3556943 (1971-01-01), Fonken et al.
patent: 3657257 (1972-04-01), Helsley et al.
patent: 4180669 (1979-12-01), Winn
patent: 4393069 (1983-07-01), Langbein et al.
patent: 4590270 (1986-05-01), Kompis et al.
patent: 4774249 (1988-09-01), Kompis et al.
patent: 5491148 (1996-02-01), Berger et al.
patent: 5859024 (1999-01-01), Hotson et al.
Archer, S., et al., J. Am. Chem. Soc., "The Action of Nucleophilic Agents on 3 .alpha.-Chlorotropane," vol. 80, 1958, pp. 4677-4681.
Bell, M.R., et al., J. Am. Chem. Soc., "Ethyl 3.alpha.-Phenyltropane-3.beta.-carboxylate and Related Compounds," vol. 82, No. 7-9, 1960, pp. 4638-4641.
Cignarella, G., et al., J. Am. Chem. Soc., "A New Synthesis of Tropane Derivatives," vol. 83, No. 10-12, 1961, pp. 4999-5003.
Daum, S. J., et al., J. Med. Chem., "Analgesic Activity of the Epimeric Tropane Analogs of Mepridine. A Physical and Pharmacological Study," vol. 18, No. 5, 1975, pp. 496-501.
Gutkowska, B., et al., Acta Polon. Pharm., "Syntezy Niektorych Pochodnych 8-Alkilo-8-Aza-Bicyklo[3.2.1]Oktan-3-Onu," vol. 38, No. 4, 1981, pp. 411-415.
Lowe, J. A., et al., J. Med. Chem., "Aza-Tricyclic Substance P Antagonists," vol. 37, No. 18, 1994, p. 2831.
Maag, H., et al., Helvetica Chimica Acta, "94. 5-(N-Arylnortropan-3-yl)- and 5-(N-Arylpiperidin-4-yl)-2,4-diaminopyrimidines. Novel Inhibitors of Dihydrofolate Reductase," vol. 69, No. 4, 1986, pp. 887-897.
Repke, D. B., et al., J. Org. Chem., "Abbreviated Ibogaine Congeners. Synthesis and Reactions of Tropan-3-yl-2- and -3-indoles. Investigation of an Unusual Isomerization of 2-Substituted Indoles Using Computational and Spectroscopic Techniques," vol. 59, No. 8, 1994, pp. 2164-2171.
Zirkle, C. L., et al., J. Org. Chem., "The Isomeric 3-Oxa- and 3-Thiagranatanin-7-ols and Their Derivatives; Reduction of Bicyclic Amino Ketones Related to Tropinone," vol. 26, 1961, pp. 395-407.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Bicyclic amine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bicyclic amine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bicyclic amine derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1336865

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.