Bicyclic 9a-azalide derivatives

Details Bicyclic 9a-azalide derivatives Bicyclic 9a-azalide derivatives

2005-09-27

2008-07-22

Peselev, Elli (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S007400

Reexamination Certificate

active

07402568

ABSTRACT:
The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof:which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

REFERENCES:
patent: 6369035 (2002-04-01), Kobrehel et al.
patent: 6645941 (2003-11-01), Wang et al.
patent: 6764996 (2004-07-01), Or et al.
patent: 6764998 (2004-07-01), Wang et al.
patent: 6852702 (2005-02-01), Kujundzic et al.
patent: 2005/0014707 (2005-01-01), Wang et al.
patent: 2005/0090460 (2005-04-01), Wang et al.
patent: 0 283 055 (1988-09-01), None
patent: WO 93/13116 (1993-07-01), None
patent: WO 98/56802 (1998-12-01), None
patent: WO 99/00124 (1999-01-01), None
patent: WO 99/00125 (1999-01-01), None
patent: WO 99/20639 (1999-04-01), None
patent: WO 02/12260 (2002-02-01), None
patent: WO 02/055531 (2002-07-01), None
patent: WO 02/068438 (2002-09-01), None
patent: WO 2004087728 (2004-10-01), None
patent: WO 2005000863 (2005-01-01), None
U.S. Appl. No. 11/008,581, filed Dec. 7, 2004, Or et al.
U.S. Appl. No. 11/324,502, filed Jan. 2, 2006, Or et al.
Bright, G. Michael, et al., “Synthesis, In Vitro and In Vivo Activity of Novel 9-Deoxo-9a-Aza-9a-Homoerythromycin A Derivatives; A New Class of Macrolide Antibiotics, the Azalides,”J. of Antibiotics, vol. XLI(8): 1029-1047 (1988).

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