Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-10-25
2005-10-25
Raymond, Richard L. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S101000
Reexamination Certificate
active
06958333
ABSTRACT:
The present invention relates to a compound of Formula (I) and the manufacturing method(s) thereof and the use thereof: wherein: Ar is a nitrogen-containing heteroaromatic ring group; X and Z are each a carbon atom, and so on; Y is CO, and so on; R1is a hydrogen atom, and so on; R2and R3are each a hydrogen atom, and so on; R4and R5are each a hydrogen atom, and so on; and the formulais a single bond or a double bond.According to the present invention, the compound of the present invention can provide Cdk4 and/or Cdk6 inhibitors for treating malignant tumors, because the compounds of the present invention exhibit a prominent growth inhibitory activity against tumor cells.
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Hayama Takashi
Hayashi Kyoko
Honma Teruki
Takahashi Ikuko
Banyu Pharmaceutical Co. Ltd.
Habte Kahsay
Raymond Richard L.
Wenderoth , Lind & Ponack, L.L.P.
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