Biaryl substituted nitrogen containing heterocycle...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S326000, C514S422000, C514S424000, C546S207000, C546S216000, C548S517000, C548S544000

Reexamination Certificate

active

07576102

ABSTRACT:
The present invention relates to a chemical genus of biaryl substituted nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula:They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

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CA Registry No. 183170-13-0, entry date into Registry file on STN is Nov. 19, 1996.
Grenier et al, CA 67:2990, 1996.
Aono et al, CA 125:328725, 1998.
Pruecher et al. CAS Accession No. 1995:501323, Year 1995.
International Search Report for PCT/US2006/030526.

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