Biaryl substituted azabicyclic alkane derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S125000, C546S126000

Reexamination Certificate

active

07902222

ABSTRACT:
The invention relates to biaryl substituted azabicyclic alkane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

REFERENCES:
patent: 2005/0043347 (2005-02-01), Betschmann et al.
patent: 2008/0045539 (2008-02-01), Ji et al.
patent: 2008/0234308 (2008-09-01), Bunnelle et al.
patent: 00/71520 (2000-11-01), None
patent: 03/062235 (2003-07-01), None
patent: 2004/037823 (2004-05-01), None
patent: 2006/101745 (2006-09-01), None
Rautio et al. Nature Reviews Drug Discovery 2008, 7, pp. 255-270.
Wang et al. Drug Delivery: Principles and Applications, 2005 John Wiley & Sons, Inc. Publication, Section 8.3, pp. 136-137.
Smith, D. A. Current Opinion in Drug Discovery & Development 2007, 10, 550-559.
Testa, B. Current Opinion in Chemical Biology 2009, 13, pp. 338-344.
Adler, E., et al., Schizophrenia Bulletin, 24(2): 189-202 (1998).
Cordero-Erausquin, M., et al., PNAS, 98(5): 2803-2807 (2001).
Friedman, J., et al., Society of Biol. Psych., 51: 349-357 (2002).
Furniss, B., et al., Vogel's Textbook of Practical Organic Chemistry, 5th edition (1989), Longman Scientific & Technical.
Greene, T.W., et al., Protecting Groups in Chemical Synthesis (3rd ed), John Wiley & Sons, NY, Table of Contents (1999).
Heeschen, C., et al., Nature Medicine, 7:833-839 (2001).
Heeschen, C., et al., J. Clin. Invest., 110:527-536 (2002).
Jonnala, R., et al., Journal of Neuroscience Research, 66: 565-572 (2001).
Kihara, T., et al., Journal of Biological Chemistry, 276: 13541-13546 (2001).
Leonard, S., et al., European Journal of Pharmacology, 393: 237-242 (2000).
Levin, E., J. Neurobiol., 53: 633-640 (2002).
Liu, Q., et al., PNAS, 98: 4734-4739 (2001).
Pabreza, L., et al., Molecular Pharmacology, 39: 9-12 (1991).
Paterson, D., et al., Progress in Neurobiology, 61: 75-111 (2000).
Prescott, D., Methods in Cell Biology, XIV: 33 et., Academic Press, New York, NY (1996).
Recommendations for Section E, Fundamental Stereochemistry, Pure and Applied Chemistry, 45:13-30 (1976).
Rollema, H., et al., Trends Pharmacological Sciences, 28(7):316-25 (2007).
Rose, J., et al., Biochem. Pharmacol., 74(8):1263-1270 (2007).
Rowley, M., et al., Journal of Medicinal Chemistry, 44(4): 477-501 (2001).
Shimohama, S., et al., Brain Research, 779: 359-363 (1988).
Solinas, M., et al., The Journal of Neuroscience, 27(21):5615-5620 (2007).
Son, J., et al., Biology of Reproduction, 68:1348-1353 (2003).
Steensland, P. et al., PNAS, 104(30): 12518-12523 (2007).
Stevens, K., Psychopharmacology, 136: 320-327 (1998).
Wang, H., et al., Nature, 421:384-388 (2003).
International Search Report dated Feb. 12, 2009.
Higuchi, T. et al., Pro-drugs as Novel Drug Delivery Systems (TOC), ACS Symposium Series vol. 14 (1975).
Wolter, M, et al., Copper-Catalyzed Coupling of Aryl Iodides with Aliphatic Alcohols, Organic Letters (2002), pp. 973-976, vol. 4(6).

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