Biaryl-pyridoquinazolinone derivatives as anti-cancer agents

Details Biaryl-pyridoquinazolinone derivatives as anti-cancer agents Biaryl-pyridoquinazolinone derivatives as anti-cancer agents

1997-11-06

1999-06-22

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514267, 544252, 540600, A61K 31505, A61K 3155, C07D47104

Patent

active

059143274

ABSTRACT:
This invention provides a compound having the formula: ##STR1## wherein: (A) n=2-4;

REFERENCES:
patent: 4033961 (1977-07-01), Schwender et al.
patent: 4104389 (1978-08-01), Schwender et al.
patent: 4348396 (1982-09-01), Kierstead et al.
patent: 4551460 (1985-11-01), Tilley
Denny et al., Structure-activity relationships for the mutagenic acitivity of tricyclic intercalating agents in Selmonella typhimurium, Mutation Research, 232 (1990) p. 233.
Ebeid et al., Synthesis and Antitumor Activity of Some N(p-Substituted Sulfamoyl-phenyl) Acridone-4-Carboxamides and N(p-substituted Egypt. J. Pharm Sci., vol.33, No. 1-2, pp. 293-303 (1992).

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