Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-06-29
2010-12-28
Desai, Rita J (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S340000
Reexamination Certificate
active
07858800
ABSTRACT:
The present invention relates to a compound represented by the formula (I):or a pharmaceutically acceptable salt thereof, wherein:R1is a linear or branched alkoxy group, a cycloalkoxy group, a linear or branched lower alkyl group, etc.; R2is halogen atom, a lower alkyl group, etc.; Q1is carbon atom or nitrogen atom; Q2is carbon atom which may be substituted with oxo group; the formula (III):in-line-formulae description="In-line Formulae" end="lead"? (II)in-line-formulae description="In-line Formulae" end="tail"?is a single bond or a double bond; A is a group selected from the group consisting of the substitutent group α; and R5is hydrogen atom, a lower alkyl group, cyano group, an alkoxy group or a trialkylsilyl group; having an mGluR1 inhibiting action and being useful as treatment and/or prevention of convulsion, acute pain, cerebral disturbance such as cerebral infarction or transient cerebral ischemia onset, anxiety, chemical dependency or Parkinson's disease.
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Supplementary European Search ReportC for EP Appl'n No. 05758117.5 (Nov. 26, 2009).
Hirata Yukari
Ito Satoru
Kawamoto Hiroshi
Kimura Toshifumi
Nagatomi Yasushi
Banyu Pharmaceutical Co. Ltd.
Desai Rita J
Devlin Gerard M.
Mabry John
Thies J. Eric
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