Biaromatic compounds which activate PPARγ type...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S364000, C514S378000, C544S098000, C546S207000, C546S226000, C548S240000

Reexamination Certificate

active

07452878

ABSTRACT:
Novel biaromatic compounds having the structural formula (I) below:are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.

REFERENCES:
patent: 6927228 (2005-08-01), Bernardon et al.
patent: 7157490 (2007-01-01), Colandrea et al.
patent: WO 00/35864 (2000-06-01), None
patent: WO 01/21584 (2001-03-01), None
patent: WO 02/12210 (2002-02-01), None
Copending U.S. Appl. No. 11/311,449, claims 1, 3, and 4.
Castanedo et al., “Solid-Phase Synthesis of Dual α4β1/α4β7 Integrin Antagonists: Two Scaffolds with Overlapping Pharmacophores”, Bioorganic & Medicinal Chemistry Letters, Oct. 2002, pp. 2913-2917, vol. 12, Elsevier Science Ltd.
Sircar et al., “Synthesis and SAR of N-benzoyl-L-Biphenylalanine Derivatives: Discovery of TR-14035, A Dual α4β7/α4β1 Integrin Antagonist”, Bioorganic & Medicinal Chemistry, Jun. 2002, pp. 2051-2066, vol. 10, Elsevier Science Ltd.
French Search Report corresponding to FR 02/14465, issued on Aug. 7, 2003, 3 pages.
International Search Report corresponding to PCT/EP 03/14861, issued on May 25, 2004, 5 pages.

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