Biaromatic compounds and pharmaceutical and cosmetic...

Details Biaromatic compounds and pharmaceutical and cosmetic... Biaromatic compounds and pharmaceutical and cosmetic...

2005-02-01

2005-02-01

Desai, Rita (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S438000, C514S456000, C514S457000, C549S013000, C549S049000, C549S398000, C544S145000, C544S147000, C546S202000

Reexamination Certificate

active

06849658

ABSTRACT:
The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R1is CH3, —CH2—O—R6, —OR6or —COR7; R2is —OR8, —SR8or a polyether radical if in the latter case R4is C1-C20alkyl and is in ortho or meta position relative to X—Ar; R3is alkyl or R2and R3together form a cycle optionally interrupted by O or S; R4is aryl radical; R5is H, halogen, C1-C20alkyl or —OR8; R6is H, alkyl or —COR9; R7is H, alkyl, —N(r′)(r″) or —OR10; R8is H, alkyl or —COR9; R9is alkyl; R10is H, C1-C20alkyl, alkenyl, monohydroxyalkyl or polyhydroxyalkyl, aryl or aralkyl or a sugar residue, r′ and r″ are H, alkyl mono- or polyhydroxyalkyl, aryl, an amino acid or sugar residue or together form a heterocycle, X represents a radical of formula (d) or (e) in which R11is H or —OR6; R12is H or alkyl; or R11and R12form an oxo radical, and the salts, optical and geometrical isomers of the compounds of formula (I).

REFERENCES:
patent: 5468879 (1995-11-01), Chandraratna
patent: 5677451 (1997-10-01), Chandraratna
patent: 5716624 (1998-02-01), Bernardon
patent: 6046220 (2000-04-01), Bernardon
patent: 6103762 (2000-08-01), Bernardon et al.
patent: 6162445 (2000-12-01), Bernardon
patent: 6313162 (2001-11-01), Bernardon
patent: 6368608 (2002-04-01), Bernardon
patent: 0661258 (1995-05-01), None
patent: 0 661 258 (1995-07-01), None
patent: WO 93 16068 (1993-08-01), None
patent: WO 93 16083 (1993-09-01), None
patent: WO 96 11902 (1996-04-01), None
Siegrist Adolf et al., Caplus 83:147317, Abstract DE 2453357, May 22, 1975.
Hiroyuki Kagechika et al., “Retinobenzoic Acids 2”, Journal of Medicinal Chemistry, vol. 32, 1989, pp. 834-840, XP000569639 Washington US see p. 834; figure 1, table II.
Abhijit Bhat et al, Tetrahedron Letters, Jan. 1999. vol. 40, Novel Synthetic Routes . . . .
Kundu et al., J. Chem. Research (S) 1995, 4-5.

Affiliated with

Also associated with

Rating

Biaromatic compounds and pharmaceutical and cosmetic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biaromatic compounds and pharmaceutical and cosmetic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biaromatic compounds and pharmaceutical and cosmetic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3450832