Bi-directional synthesis of oligoguanidine transport agents

Details Bi-directional synthesis of oligoguanidine transport agents Bi-directional synthesis of oligoguanidine transport agents

2006-06-27

2006-06-27

Lukton, David (Department: 1654)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S020800, C514S565000, C554S053000, C564S230000, C564S236000, C530S333000, C530S345000

Reexamination Certificate

active

07067698

ABSTRACT:
Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.

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