Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
1997-11-17
2001-07-10
Celsa, Bennett (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S018700, C514S336000, C514S345000, C514S433000, C514S444000, C514S445000, C514S452000, C514S473000, C514S475000, C546S268400, C546S290000, C549S059000, C549S062000, C549S475000, C549S483000, C549S331000, C549S014000, C549S357000, C564S253000, C564S254000, C564S300000, C568S027000, C568S028000, C536S055200, C424S070210, C540S001000
Reexamination Certificate
active
06258775
ABSTRACT:
BRIEF DESCRIPTION OF THE INVENTION
The invention relates to biaromatic compounds, as novel and useful industrial products. The invention also relates to the use of these novel compounds in pharmaceutical compositions intended for use in human or veterinary medicine, or alternatively in cosmetic compositions.
The compounds according to the invention have pronounced activity in the fields of cell differentiation and proliferation, and find applications more particularly in the topical and systemic treatment of dermatological complaints associated with a keratinization disorder, dermatological (or other) complaints with an inflammatory and/or immunoallergic component, and dermal or epidermal proliferations, whether these are benign or malignant. These compounds can also be used in the treatment of degenerative diseases of connective tissue, to combat ageing of the skin, both photoinduced and chronological ageing, and to treat cicatrization problems. They moreover find an application in the ophthalmological field, in particular in the treatment of corneopathies.
REFERENCES:
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patent: 5476873 (1991-05-01), Brooks et al.
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Kuo-Long Yu: “Application of the Heck reaction in the synthesis of truncated naphthoic acid retinoids”, Bioorganic & Medicinal Chemistry Letters, vol. 6, No. 23, 1996, pp. 2859-2864, XP002061556.
Uspatfull 95:112558 to US Pat No. 5476873 and Reg. No. 141581-11-5, Dec. 1995.
Bernardon Jean-Michel
Diaz Philippe
Burns Doane Swecker & Mathis L.L.P.
Celsa Bennett
Centre International de Recherches Dermatologiques Galderma
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