Bi-4-[1-(quinazolinyl-4)piperidyls] and bis{4-[1-(quinazolinyl-4

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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2602564Q, 2602565R, 26029363, 2603403, C07D40114

Patent

active

040113230

ABSTRACT:
Disclosed are bi-4-[1-(quinazolinyl-4)piperidyls] and bis{4-[1-(quinazolinyl-4)piperidyl]alkanes}, e.g. 1,3-bis{4-[1-(6,7-dimethylquinazolinyl-4)piperidyl]propane}, having pharmacological activity in animals and useful for example, as anti-obesity and anti-diabetic agents. Said compounds may be prepared by reacting a 4-haloquinazoline with bi-4-piperidyl or a bis(piperidyl-4)alkane.

REFERENCES:
patent: 3931179 (1976-01-01), Simpson
patent: 3971783 (1976-07-01), Barnish et al.
Tietz, "Clinical Chemistry," pp. 153, 807-808.
White et al., "Principals of Biochemistry," (1968) pp. 974-977.

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