Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-03-21
2008-11-25
Bunner, Bridget E. (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S069100, C435S320100, C435S471000, C435S325000, C424S084000
Reexamination Certificate
active
07456256
ABSTRACT:
The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
REFERENCES:
patent: WO0075358 (2000-12-01), None
patent: WO0157262 (2001-08-01), None
patent: WO0160850 (2001-08-01), None
patent: WO0222802 (2002-03-01), None
Wells, 1990, Biochemistry 29:8509-8517.
Lazar et al, 1988, Mol. Cell. Biol., vol. 8, pp. 1247-1252.
NCBI Entrez Accession No. XP—0601006 (gi:17434070) NCBI Annotation Project, Aug. 1, 2002.
NCBI Entrez Accession No. XP—088446 (gi:18571999) NCBI Annotation Project, Aug. 1, 2002.
Cheng Janet D.
Feder John N.
Krystek, Jr. Stanley R.
Lee Liana M.
Wu Shujian
Bristol--Myers Squibb Company
Bunner Bridget E.
Hamud Fozia M
Parlet Nickki L.
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