bFGF mutein and its production

Details bFGF mutein and its production bFGF mutein and its production

1994-04-22

1998-12-22

Allen, Marianne P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530399, 536 235, 435 694, 4352402, 4352523, 4353201, C12N 1518, A61K 3818, C07K 1450

Patent

active

058519904

ABSTRACT:
A mutein resulting from substitution of cysteins for at least one of the constitutional amino acids has a high stability, and can serve well as a pharmaceutical, such as a healing promoting agent for wounds.

REFERENCES:
patent: 4518584 (1985-05-01), Mark et al.
patent: 4588585 (1986-05-01), Mark et al.
patent: 4853871 (1989-08-01), Pantoliano et al.
patent: 4959314 (1990-09-01), Mark et al.
patent: 5130418 (1992-07-01), Thompson
patent: 5155214 (1992-10-01), Baird et al.
Abraham et al. EMBOJ. 5(10):2523-28 (1986).
Zhu et al., Science, 251 :90-93, 1991.
Zhang et al., PNAS :3446-3450, 1991.

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