Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-04-27
1996-06-18
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 435968, 436501, 436503, 436504, 436815, 536 231, 536 235, 536 2431, 935 76, 935 77, 935 78, C12Q 168, G01N 3353, C07H 2104, C12N 1500
Patent
active
055276792
ABSTRACT:
In accordance with the present invention, a cDNA clone encoding a new human .beta. subunit which was designated .beta..sub.5 was found. Probes for this nucleotide sequence are described. In addition, the .beta..sub.5 protein, its associated subunit and its cell distribution were characterized. In another embodiment, this invention relates to assays for detecting this protein. .beta..sub.5 subunit was found present on carcinomas, but absent from lymphoid cells. Consequently, this protein can be used to determine the presence of carcinoma.
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Hemler Martin E.
Ramaswamy Hemavathi
Conlin David G.
Dana Farber Cancer Institute
Eisenstein Ronald I.
Jones W. Gary
Resnick David S.
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