Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-12-23
1994-07-26
Higel, Floyd D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
544324, 544335, 544374, 546293, 546331, 5483255, 548205, 548235, 5482678, 548559, 564 74, 564 78, C07C32738, C07C32748, C07D23396, A61K 31165
Patent
active
053328337
ABSTRACT:
The .beta.-oxo-.beta.-benzenepropanethioamide derivative of the present invention has potassium channel opening action and is useful for treatment of hypertension, asthma, hypersensitive colon syndrome, and enteritis through pharmacological actions including blood vessel dilation, bronchial tract dilation, relaxation of gastrointestinal tract smooth muscle, and the like. The present invention also includes a pharmaceutical composition containing, as the active ingredient, the compound of the present invention and a method for producing the same.
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Yates et al., Tetrahedron, vol. 44, No. 11, pp. 3159-3170 (1988).
Hayashi Junko
Nagano Tatsuo
Seino Asami
Sekiya Tetsuo
Shimpuku Tetsuro
Higel Floyd D.
Mitsubishi Kasei Corporation
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