.beta.-Lactams

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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Details

260239A, 2603309, 549451, 564443, C07D20508, C07D40304, C07D40504, C07D40514

Patent

active

045767513

ABSTRACT:
There is presented optically uniform .beta.-lactams of the formulae ##STR1## wherein Z is a readily cleavable acyl group, R.sup.1 is amino or a group convertible into amino, R.sup.2 is hydrogen or a readily cleavable protecting group and R.sup.3 and R.sup.4 each are a lower hydrocarbon group which optionally contains oxygen and which is attached via a carbon atom, whereby these groups can also be joined with one another to form a ring, with the proviso that R.sup.1 is a readily cleavable acylamino when R.sup.2 is hydrogen,
and the corresponding optical antipodes, their manufacture and use in the manufacture of antimicrobially-active .beta.-lactams as well as novel intermediates usable in their manufacture.

REFERENCES:
patent: 4473502 (1984-09-01), Liv et al.

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