Beta-lactamase inhibiting 6-(alkoxyamino-methyl) penicillanic ac

Details Beta-lactamase inhibiting 6-(alkoxyamino-methyl) penicillanic ac Beta-lactamase inhibiting 6-(alkoxyamino-methyl) penicillanic ac

1983-06-06

1985-02-12

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602452T, C07D49900, A61K 31415

Patent

active

044990170

ABSTRACT:
6-alpha/beta-[(C.sub.1 -C.sub.4)Alkoxyaminomethyl and benzyloxyaminomethyl]penicillanic acid 1,1-dioxides, pharmaceutically acceptable salts thereof and conventional esters thereof hydrolyzable under physiological conditions, all of which are useful in medicine as beta-lactamase inhibitors; intermediates and processes therefor; and a process for the conversion of the present compounds to 6-alpha- and 6-beta-(aminomethyl)penicillanic acid 1,1-dioxides and derivatives.

REFERENCES:
patent: 4234579 (1979-03-01), Barth
patent: 4287181 (1981-09-01), Kellogg

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