Beta lactam production

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540230, 540215, 540301, 540205, C07D50118, C07D50157, C07D49802

Patent

active

056080557

ABSTRACT:
A new process is described for the production of 7-alpha-aminoacyl-cephalosporin free from halogen-containing solvents by acylating 7-amino-ceph-3-em-4-carboxylic acid or a derivative thereof in a halogen-free solvent.

REFERENCES:
patent: 4073902 (1978-02-01), Scartazzini
patent: 4358588 (1982-11-01), Henniger
patent: 4358988 (1982-11-01), Henniger
J. Med. Chem., vol. 9, 746 (1966) Spencer, et al.
C.A.91(1):5236v, Juste Sese(1979).
CA 85 (23):177405s, Hebron, S. A. (1976).
CA 86 (9):55467p. Juste (1977).
CA 89 (13):109467w, Cuixart Grande (1978).
CA 106:119004b, Cabri, et al. (1987).

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