Beta lactam production

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540221, 540302, C07D48700, C07D49904, C07D50120

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active

057192766

ABSTRACT:
A new process is described for the production of 6-alpha-amino-penicillins and 7-alpha-amino-desacetoxy-cephalosporins free from halogen-containing solvents by acylating 6-APA, 7-ADCA or a derivative thereof in a halogen-free solvent.

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J.L. Spencer, et al., J. Med. Chem. 9, 746 (1966).
J. Cabre-Castellvi, et al., Afinidad 43, 421 (1986.
Chemical Abstracts vol. 106, 1987--106:119004b.
CA 85; 177, 405 s; 1976.
CA 86; 55467 p; 1976.
CA 91; 5236 v; 1978.

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