.beta.-Lactam precursors of penicillin and cephalosporin antibio

Details .beta.-Lactam precursors of penicillin and cephalosporin antibio .beta.-Lactam precursors of penicillin and cephalosporin antibio

1977-12-29

1979-04-03

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602391, 424246, C07D27504

Patent

active

041476999

ABSTRACT:
This invention provides novel .beta.-lactam precursors of known and novel microbiologically active penicillins and cephalosporins and to a process for making the .beta.-lactam precursors from a L-cysteinylvaline dipeptide or a polypeptide containing the L-cysteine with other amino acids. The .beta.-lactam precursors are represented by the Formula I. ##STR1## wherein Z is ##STR2## and wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are defined herein. When Z has the structure of Formula A, the .beta.-lactam is a precursor for cephalosporins. When Z has the structure of either Formula B or Formula C, the .beta.-lactam is a precursor for a penicillin.

REFERENCES:
patent: 3799938 (1974-03-01), Seusler et al.
patent: 3862164 (1975-01-01), Cooper
patent: 3900487 (1975-08-01), Underwood et al.

Affiliated with

Also associated with

Rating

.beta.-Lactam precursors of penicillin and cephalosporin antibio does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with .beta.-Lactam precursors of penicillin and cephalosporin antibio, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .beta.-Lactam precursors of penicillin and cephalosporin antibio will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1746228