.beta.-Lactam antibiotics, their preparation and use

Details .beta.-Lactam antibiotics, their preparation and use .beta.-Lactam antibiotics, their preparation and use

1982-02-03

1983-10-18

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602452T, 424274, 544316, 544317, 544319, 544320, C07D48704, A61K 31505

Patent

active

044105339

ABSTRACT:
The present invention provides a compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt or in-vivo hydrolyzable ester thereof wherein R.sup.1 is a hydrogen atom, an .alpha.-sulphonato-oxyethyl group, an .alpha.-sulphonato-oxypropyl group or is a group CR.sup.3 R.sup.4 R.sup.5 wherein R.sup.3 is a hydrogen atom or a hydroxy group; R.sup.4 is a hydrogen atom or a C.sub.1-6 alkyl group; and R.sup.5 is a hydrogen atom or a C.sub.1-6 alkyl group, a benzyl group, a phenyl group or is joined to R.sup.4 to form together with the carbon atom to which they are joined a carbocyclic ring of 5 to 7 carbon atoms; R.sup.2 is a pyrimidinyl group substituted by one two or three groups selected from nitro, halo, amino or substituted amino, and in addition may be optionally substituted by one or two C.sub.1-6 alkyl groups as the degree of substitution permits; and x is zero or one.
These compounds are antibacterial agents. Their preparation and use are described.

REFERENCES:
patent: 4189493 (1980-02-01), Christensen et al.
patent: 4309346 (1982-01-01), Christensen et al.
patent: 4323569 (1982-04-01), Baxter
patent: 4337199 (1982-06-01), Yoshioka et al.
patent: 4347367 (1982-08-01), Christensen et al.

Affiliated with

Also associated with

Rating

.beta.-Lactam antibiotics, their preparation and use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with .beta.-Lactam antibiotics, their preparation and use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .beta.-Lactam antibiotics, their preparation and use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1289345