Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1981-10-13
1984-03-20
Lee, Mary C.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424274, 424269, 424270, 424273R, 424114, 544 36, C07D48704
Patent
active
044380364
ABSTRACT:
The present invention provides a process for inversion of the absolute stereochemistry at the .alpha.-carbon atom of a C-6 substituent of a bicyclic carbapenem antibiotic via a phosphorus - azodicarboxylate mediated reaction. Novel azides, amines and formates are described as useful intermediates and as antibacterial agents.
Corbett David F.
Coulton Steven
Southgate Robert
Beecham Group Limited
Lee Mary C.
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