Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1979-03-30
1982-12-28
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
2602452T, A61K 3140, C07D48704
Patent
active
043661670
ABSTRACT:
This invention provides the anti-bacterial compounds (III) and (IV): ##STR1## and salts and esters thereof wherein X is a --CH.sub.2 --CH.sub.2 -- or trans --CH.dbd.CH-- group and R is a group R.sup.1 or NH.R.sup.1 wherein R.sup.1 is an alkyl group of up to 6 carbon atoms, an alkenyl group of up to 6 carbon atoms, an aryl group, or an alkyl group of up to 6 carbon atoms substituted by an aryl or aryloxy group.
The invention also provides processes for their preparation comprising a the acylation or carbamoylation of the corresponding 6-(1-hydroxyethyl) compounds.
The invention further provides pharmaceutical compositions containing them.
REFERENCES:
patent: 4162323 (1979-07-01), Kahan
patent: 4162324 (1979-07-01), Cassidy et al.
patent: 4163051 (1979-07-01), Box et al.
patent: 4196211 (1980-04-01), Christensen et al.
patent: 4208330 (1980-06-01), Christensen et al.
patent: 4226870 (1980-10-01), Christensen et al.
Morrison et al.; Organic Chemistry; pp. 526, 671-672, 927 (1969).
Beecham Group Limited
Berch Mark L.
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