.beta.-Lactam antibiotics

Details .beta.-Lactam antibiotics .beta.-Lactam antibiotics

1976-12-20

1978-06-06

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239A, 424271, 424272, C07D49804

Patent

active

040936260

ABSTRACT:
Compounds of the formula ##STR1## wherein R is hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, epoxide of 2 to 4 carbon atoms or alkyl of 1 to 4 carbon atoms substituted by 1 or 2 halogen atoms, hydroxyl, etherified or acylated hydroxyl of 1 to 7 carbon atoms, azido, phthaliamido, SR.sup.1, SOR.sup.1 or SO.sub.2 R.sup.1 wherein R.sup.1 is aryl, are useful for their .beta.-lactamase inhibitory activity and their antibacterial activity.

REFERENCES:
patent: 3334095 (1967-08-01), Houlihan

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