.beta.-lactam antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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2602391, A61K 3143, C07D49914

Patent

active

045980748

ABSTRACT:
Alpha-carboxy-3-thienylmethyl penicillin having either the R- or the S- configuration at C-10 is obtained in cyrstalline form. The isomers show improved stability and higher biological activity as compared to the amorphous RS material.

REFERENCES:
patent: 4081546 (1978-03-01), Ferres
patent: 4171303 (1979-10-01), Huhn et al.
V. DasGupta et al, "Quantitation of . . . Ticarcillin Disodium by HPLC", J. Pharm. Sci., 69, No. 11, 1264-1267 (Nov. 1980).

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