Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-05-02
1986-07-01
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
2602391, A61K 3143, C07D49914
Patent
active
045980748
ABSTRACT:
Alpha-carboxy-3-thienylmethyl penicillin having either the R- or the S- configuration at C-10 is obtained in cyrstalline form. The isomers show improved stability and higher biological activity as compared to the amorphous RS material.
REFERENCES:
patent: 4081546 (1978-03-01), Ferres
patent: 4171303 (1979-10-01), Huhn et al.
V. DasGupta et al, "Quantitation of . . . Ticarcillin Disodium by HPLC", J. Pharm. Sci., 69, No. 11, 1264-1267 (Nov. 1980).
Andreescu George
Clark Dennis E.
Kerr William J.
Beecham Group p.l.c.
Clarke Vera C.
Trousof Natalie
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