.beta.-Lactam antibacterial agents

Details .beta.-Lactam antibacterial agents .beta.-Lactam antibacterial agents

1982-07-23

1985-09-03

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602452R, 544 19, 544 21, 544 90, 546183, C07D49950, C07D49954, C07D50124

Patent

active

045391491

ABSTRACT:
.beta.-Lactam antibiotics having an .alpha.-formamido substituent on the carbon atom adjacent to the carbonyl group of the .beta.-lactam ring and in particular bicyclic compounds having the partial structure: ##STR1## Intermediates and processes for the preparation of the compounds are further disclosed.

REFERENCES:
patent: 3974150 (1976-08-01), Cook et al.
patent: 4281117 (1981-07-01), Chauvette et al.
Transformations Using Benzyl 6-Isocyanopenicillanate, P. H. Bentley et al., JCS Perkin I (1979), pp. 2455-2467.
6.alpha.-Substituted Penicillins, P. H. Bentley et al., JCS Chem. Comm. (1974), pp. 278-279.

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