Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1981-09-28
1983-09-20
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
260239A, 2602452T, 424114, C07D48704, A61K 3140
Patent
active
044056370
ABSTRACT:
Compounds are described of the formula (II): ##STR1## wherein R.sub.1 is a group such that CO.sub.2 R.sub.1 is an ester group; A.sub.1 is a hydrogen atom; and A.sub.2 is a group CR.sub.2 R.sub.3 R.sub.4 wherein R.sub.2 is a hydrogen atom or a hydroxyl group; R.sub.3 is a hydrogen atom or a lower alkyl group; and R.sub.4 is a hydrogen atom or a lower alkyl group, a benzyl group, a phenyl group or is joined to R.sub.3 to form part of a C.sub.5-7 carboxylic ring or is a group of the formula CH(OH)R.sub.5 or CHX wherein R.sub.5 is a hydrogen atom or lower alkyl group and X is an oxygen atom or a CR.sub.6 R.sub.7 group where R.sub.6 is a hydrogen atom or a lower alkyl, phenyl, CN, CO.sub.2 R.sub.8 where R.sub.8 is a lower alkyl, phenyl or benzyl group and R.sub.7 is a hydrogen atom or a lower alkyl group or is joined to R.sub.6 to form part of a C.sub.5-7 carbocyclic ring. These compounds have been found to possess antibacterial properties. The preparation of these compounds is described.
REFERENCES:
patent: 4196211 (1980-04-01), Christensen et al.
patent: 4203902 (1980-05-01), Shih
patent: 4289696 (1981-09-01), Small
patent: 4350703 (1982-09-01), Dickinson et al.
Dickinson nee Berryman Kay H.
Smale Terence C.
Southgate Robert
Beecham Group Limited
Lee Mary C.
LandOfFree
.beta.-Lactam antibacterial agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with .beta.-Lactam antibacterial agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and .beta.-Lactam antibacterial agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-588090