.beta.-Lactam anti-bacterial, compositions containing them and a

Details .beta.-Lactam anti-bacterial, compositions containing them and a .beta.-Lactam anti-bacterial, compositions containing them and a

1979-08-23

1982-04-06

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602452T, 260239A, 544316, 544319, C07D48704, A61K 31505

Patent

active

043235697

ABSTRACT:
The compounds of the formula (II): ##STR1## and salts and esters thereof wherein R.sub.1 is a pyrimidyl group, or a pyrimidyl group substituted by one or two lower alkyl groups, or by a lower alkoxy group or by a lower acyloxy group; and R.sub.2 is a hydrogen atom or a group CR.sub.3 R.sub.4 R.sub.5 wherein R.sub.3 is a hydrogen atom or a hydroxy group; R.sub.4 is a hydrogen atom or a lower alkyl group; and R.sub.5 is a hydrogen atom or a lower alkyl group, a benzyl group, a phenyl group or is joined to R.sub.4 to form part of a C.sub.5-7 carbocyclic ring, have been found to be anti-bacterial-agents. Their preparation and use is described.

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