Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1985-03-04
1988-09-06
Brown, J. R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 11, 536120, 514 23, A61K 3170, C07H 1504
Patent
active
047693630
ABSTRACT:
A novel beta-1,3-glucan (ganoderan) is produced by culturing a microorganism of genus Ganoderma. Ganoderan is composed of a backbone structure of beta-1,3-linked D-glucopyranose residues bearing, at some of the C-6 positions, side chains of single beta-1,6-linked D-glucopyranose residue, and, at some of the C-2 positions, side chains of another type wherein 2-4 D-glucopyranose residues are linked via beta-1,4-linkage. Hydrogenation of ganoderan leads to the formation of a polyol-type ganoderan. Intact- and polyol-type ganoderans both having a strong antioncotic activity. They are usable in chemicals, food products, pharmaceuticals, etc.
REFERENCES:
patent: 4202966 (1980-05-01), Misaki et al.
patent: 4306059 (1981-12-01), Yokobayashi et al.
patent: 4430322 (1984-02-01), Stoudt et al.
patent: 4603197 (1986-07-01), Kadoya et al.
Cram et al., Organic Chemistry, 2nd Ed., 1964, pp. 300, 416 and 633-634.
Misaki Akira
Sone Yoshiaki
Takeuchi Kanou
Yoshida Mikihiko
Brown J. R.
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Peselev Elli
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