Beta, gamma-dihydropolyprenyl alcohol derivatives and pharmaceut

Details Beta, gamma-dihydropolyprenyl alcohol derivatives and pharmaceut Beta, gamma-dihydropolyprenyl alcohol derivatives and pharmaceut

1996-01-11

2000-08-29

Kight, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

568687, 568875, 5689095, C07C 6976, C07C 4300, C07C 3500

Patent

active

061111317

ABSTRACT:
A .beta.,.gamma.-dihydropolyprenyl alcohol derivative having the formula: ##STR1## wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a prophylactic therapeutic agent for human and animal immuno-deficiency deseases and phylactic agent against human and animal infectious deseases. Another disclosed polyprenyl compound is also useful as the same agent.

REFERENCES:
patent: 4199587 (1980-04-01), Kijima et al.
patent: 4325974 (1982-04-01), Yamamoto et al.
Ogura et al, JP 53127889 (abstract) Nov. 8, 1979 "all trans-type polyprenyl alcohol". 1978.
Krajewska, I., et al. "Uptake and Metabolism of Polyprenols by Animal Cells Cultured in vitro", Biosci. Rep., 1(12), pp. 893-902, 1981).
Bioscience Reports 1, 893-902 (1981), Uptake and Metabolism of Polyprenols by Animal Cells Cultured In Vitro, Izabella Krajewska and W. Jankowski.

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