.beta.-Endorphin analog

Details .beta.-Endorphin analog .beta.-Endorphin analog

1977-06-30

1978-07-04

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

040987787

ABSTRACT:
The .beta.-endorphin analog .beta.-endorphin (6-31), although lacking the enkephalin moiety i.e., .beta.-endorphin (1-5) exhibits analgesic activity which is not reversed by naloxone.

REFERENCES:
li, et al., Biochem. and Biophys. Res. Commun. 75, 1977, pp. 576-580.
Lazarus, et al., Proc. Nat'l. Acad. Sci USA 73, pp. 2156-2159, 1976.
Ling, et al., Proc. Nat'l. Acad. Sci USA 73, pp. 3308-3310, 1976.
Snyder, et al., Journal of Neurochem. 28, 1977, pp. 13-20.

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