.beta.-cyclodextrin complexes of miconazole and econazole

Details .beta.-cyclodextrin complexes of miconazole and econazole .beta.-cyclodextrin complexes of miconazole and econazole

1990-09-05

1995-06-06

Marx, Irene

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536103, C08B 3716, A01N 4304

Patent

active

054223474

ABSTRACT:
The econazole and miconazole complexes with .beta.-cyclodextrin show in vitro a good anti-fungal activity with a wide spectrum and, if locally applied, are well tolerated and more effective than the corresponding nitrates for the control, in vivo and clinically, of mycosis as induced from dermatophytes and from Candida albicans.

REFERENCES:
patent: 3459731 (1969-08-01), Gramera et al.
patent: 4764604 (1988-08-01), Muller
Van Doorne et al., Proc. 4th Int. Symp. Cyclodextrin Apr. 20-22, 1988, Ed. Huber.
Franko et al., Tag. Ber. Akad. Landwirtsch. Wiss, DDR (1987), 253, 311-314.
Van Doorne et al, Pharm. Weeklad Sci. Ed. 1988, vol. 10, pp. 80-85.

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