Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-05-31
2011-05-31
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S232800, C514S235200, C544S121000, C544S127000, C544S130000, C544S131000, C544S132000, C544S140000, C544S142000
Reexamination Certificate
active
07951801
ABSTRACT:
This invention provides beta-carboline compounds of formula III-A-aa:wherein Q, G, R1, R2, R3, and R6bare as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.
REFERENCES:
patent: 6627637 (2003-09-01), Ritzeler et al.
patent: 2004/0110759 (2004-06-01), Ritzeler et al.
patent: 2004/0235839 (2004-11-01), Hepperle et al.
patent: 19951360 (2001-05-01), None
patent: WO 00/09492 (2000-02-01), None
patent: WO 01/68648 (2001-09-01), None
patent: WO 03/024936 (2003-03-01), None
patent: WO 03/039545 (2003-05-01), None
patent: WO 2004/092167 (2004-10-01), None
International Search Report issued in PCT Application No. PCT/US05/013812, which corresponds to U.S. Appl. No. 11/101,998, (2005).
Castro, Alfredo C. et al., “Novel IKK Inhibitors: β-Carbolines,”Bioorganic&Medicinal Chemistry Letters, vol. 13, No. 14 (2003), pp. 2419-2422.
Hottelet, M. et al., “Development of IκB Kinase Inhibitors as Anti-Inflammatory Therapeutics,”Inflammation Research, Birkhaeuser Verlag, vol. 49, No. Supplement 2 (Sep. 24, 2000), p. S91 (Abstract).
Lee, Michael et al., “Down-Regulation of Protein Kinase C in Murine Splenocytes: A Potential Mechanism for 2-Acetylaminofluorene-Mediated Immunosuppression,”Cancer Letters, vol. 101, No. 1 (1996), pp. 53-57.
Palanki, Moorthy S.S., “Inhibitors of AP-1 and NF-κB Mediated Transcriptional Activation Therapeutic Potential in Autoimmune Diseases and Structural Diversity,”Current Medicinal Chemistry, vol. 9, No. 2 (Jan. 2002), pp. 219-227.
Fleming Paul E.
Harriman Geraldine C. B.
Hepperle Michael E.
Little Jeremy D.
Liu Julie Fields
Anderson Rebecca L
Millennium Pharmaceuticals Inc.
LandOfFree
Beta-carbolines useful for treating inflammatory disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Beta-carbolines useful for treating inflammatory disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Beta-carbolines useful for treating inflammatory disease will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2639722