.beta.-Carboline-derived compounds, lamchart benzodiazepine-rece

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546 64, C07D21381, A61K 31435

Patent

active

052583856

ABSTRACT:
The invention relates to novel .beta.-carboline-derived compounds which are benzodiazepine-receptor ligands having an inverse agonist and antagonist effect on benzodiazepines. These compounds are of the formulae: ##STR1## in which: X is O, S, ##STR2## or alternatively, ##STR3## represents the radical --N(R.sub.6)--C(=O)--CH.sub.2 --X, R.sub.1 is a hydroxyl, alkoxy or alkyl radical substituted by a hydroxyl or alkoxy radical,

REFERENCES:
patent: 3644384 (1972-02-01), Schulenberg
Mann et al., J. of Chem. Soc., Part XIII, pp. 3830-3833, 1959.

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