Beta-blocking oxindole derivatives

Details Beta-blocking oxindole derivatives Beta-blocking oxindole derivatives

1986-12-30

1989-05-02

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514274, 514323, 514339, 514359, 514381, 514383, 514386, 514392, 514397, 514403, 514406, 514409, 514414, 514418, 544310, 544333, 546201, 546273, 548253, 548255, 548262, 548269, 548301, 548318, 548336, 548371, 548372, 548374, 548411, 548455, 548467, 548486, A61K 31505, C07D40106, C07D40306

Patent

active

048268470

ABSTRACT:
The present invention provides oxindole derivatives of the formula: ##STR1## wherein the various substituents are defined hereinbelow. The above compounds display nitrate-like as well as .beta.-blocking actions.

REFERENCES:
patent: 3825558 (1974-07-01), Seemann
patent: 3882143 (1975-05-01), Seemann
patent: 4115409 (1978-09-01), Large et al.
patent: 4161530 (1979-07-01), Koella
patent: 4256890 (1981-03-01), Nakagawa et al.
patent: 4287194 (1981-09-01), Kosa et al.
patent: 4288452 (1981-09-01), Sombroek et al.
patent: 4317832 (1982-03-01), Klingler et al.
patent: 4642309 (1987-02-01), Michel et al.
Burger's Medicinal Chemistry, 4th Edit., Part III, 1981, pp. 310-316.

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