Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1998-12-31
2000-06-06
Peselev, Elli
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 74, 536 185, A61K 3170, C07H 1708
Patent
active
060718862
ABSTRACT:
The present invention relates to .beta.,.beta.-disubstituted derivatives of 9-deoxo-9a-N-ethenyl-9a-aza-9a-homoerythromycin A, new semisynthetic antibiotics of macrolide class of the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are mutually the same or different and represent nitrile, carboxy group of the formula COOR.sup.3, wherein R.sup.3 represents C.sub.1 -C.sub.4 alkyl group, or keto group of the formula COR.sup.4, wherein R.sup.4 represents C.sub.1 -C.sub.4 alkyl group, to their pharmaceutically acceptable addition salts with inorganic or organic acids, to a process for the preparation thereof, to a process for the preparation of pharmaceutical compositions, as well as to the use of the obtained pharmaceutical compositions in the treatment of bacterial infections.
REFERENCES:
patent: 5629296 (1997-05-01), Kujundzic et al.
Kelneric Zeljko
Kobrehel Gabrijela
Kujundzic Nedjeljko
Lazarevski Gorjana
Pavlovic Dina
Peselev Elli
Pliva Farmaceutska, Kemijska, Prehrambena I Kozmeticka Industrij
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