.beta.-Aminoacid derivatives and process for production thereof

Details .beta.-Aminoacid derivatives and process for production thereof .beta.-Aminoacid derivatives and process for production thereof

1984-03-05

1985-03-19

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549342, 549454, C07D31700

Patent

active

045060851

ABSTRACT:
A compound represented by the formula ##STR1## wherein R.sup.1 represents a lower alkyl group, a phenyl group or a benzyl group, or the two R.sup.1 groups together represent a group of the formula --CH.sub.2 --.sub.n in which n is an integer of 4 to 7; R.sup.2 represents a hydrogen atom, an alkyl group, or a substituted or unsubstituted aralkyl group; and Z represents a hydrogen atom, a lower alkyl group or a substituted or unsubstituted benzyl group;
and a process for production thereof. The compounds of this invention are useful as intermediates for the synthesis of various biologically active substances, such as various antibiotics, particularly .beta.-lactam antibiotic derivatives, thienamycin, antibiotic PS-5 and their analogous substances.

REFERENCES:
patent: 4424370 (1984-01-01), Kleeman et al.
Tetrahedron Letters, vol. 21, pp. 2783-2786, (1980).
Tetrahedron Letters, vol. 22, pp. 913-916, (1981).
Chem. Pharm. Bull., 30(5), 1929-1931, (1982).

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