.beta.-3-Amino nor-tropane compounds

Details .beta.-3-Amino nor-tropane compounds .beta.-3-Amino nor-tropane compounds

1980-09-11

1984-01-03

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424265, 544320, 544321, 546125, C07D45100, A61K 3146

Patent

active

044243588

ABSTRACT:
There are disclosed nor-tropane derivatives substituted at the 3 position with aroylamino or heteroaroylamino and substituted at the 8 position with benzyl, substituted benzyl, 2-methyl thiophene, 3-methyl thiophene, 2-methyl furan or cyclohexylmethyl. The compounds are prepared by condensing the carboxylic acids corresponding to said aroyl or heteroaroyl group with the corresponding .beta.-3-amino-8-substituted nor-tropanes. The compounds possess neuroleptic properties.

REFERENCES:
patent: 2800483 (1957-07-01), Jucker et al.
patent: 2893996 (1959-07-01), Rundner et al.
patent: 3134782 (1964-05-01), Archer et al.
patent: 4179567 (1979-12-01), Clarke et al.
patent: 4273778 (1981-06-01), Hadley et al.

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