.beta.(1-3)-glucan diagnostic assays

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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5361231, 435 72, 436501, C07H 100

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active

060840927

ABSTRACT:
Methods of isolating .beta.(1-3)-glucan or .beta.(1-3)glucan-containing organisms in a sample, or of detecting the presence of .beta.(1-3)-glucan or .beta.(1-3)-glucan-containing organisms in a sample, utilizing binding agents for .beta.(1-3)-glucan, such as LacCer, GalCer, globotriaosylceramide and asialoganglioside-GM1, are described. Methods of diagnosing fungal infection, by detecting .beta.(1-3)-glucan or .beta.(1-3)-glucan-containing organisms, are also described. Antibodies and kits useful in the methods are also disclosed.

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