Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-03
2006-10-03
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S217040, C514S236800, C514S253010, C514S255050, C514S278000, C514S307000, C514S316000, C514S318000, C514S323000, C540S597000, C544S129000, C544S364000, C544S405000, C546S016000, C546S144000, C546S187000, C546S194000, C546S201000, C546S209000, C546S211000
Reexamination Certificate
active
07115635
ABSTRACT:
The object of the present invention is to provide a compound having a treatment effect based on a chemokine inhibitory activity, which is satisfactory as a pharmaceutical product for oral administration.The present inventors have found that the following benzylpiperidine derivative (the formula (1)) has a chemokine inhibitory activity. Further intensive studies have resulted in successful enhancement of the chemokine inhibitory activity and stability in blood of the present compound, as well as the completion of the present invention.wherein each symbol is as defined in the specification.
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Higashi Hidemitsu
Kiuchi Masatoshi
Kuroita Takanobu
Kuwahara Shigeki
Takeda Shuuzou
Chang Celia
Mitsubishi Pharma Corporation
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