Benzylidene rhodanines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

548183, C07D27734, A61K 31425

Patent

active

057475172

ABSTRACT:
This invention provides novel benzylidene rhodanines which are useful as agents in treating or preventing conditions associated with .beta.-amyloid peptide. This invention further provides methods of treating or preventing Alzheimer's Disease which comprises administering to a mammal in need thereof an effective amount of one or more of the benzylidene rhodanines of the present invention.

REFERENCES:
patent: 4287200 (1981-09-01), Kawamatsu et al.
patent: 4376777 (1983-03-01), Kawamatsu et al.
patent: 4387101 (1983-06-01), Kawamatsu et al.
patent: 4461902 (1984-07-01), Kawamatsu et al.
patent: 4552891 (1985-11-01), Ho et al.
patent: 4617312 (1986-10-01), Schnur
patent: 4636516 (1987-01-01), Kubo et al.
patent: 4703052 (1987-10-01), Eggler et al.
patent: 4714765 (1987-12-01), Ogawa
patent: 4863923 (1989-09-01), Ho et al.
patent: 4948900 (1990-08-01), Iijima et al.
patent: 4997948 (1991-03-01), Zask et al.
patent: 5158966 (1992-10-01), Lafferty et al.
patent: 5208250 (1993-05-01), Ceterko
patent: 5523314 (1996-06-01), Rue-Valleskey
H.J. Teuber, et al., Liebigs Ann. Chem, 757 (1978).
Katsumi, et al., Chem. Pharm. Bull, 34:1619 (1986).
Chakrabati, et al., Tetrahedron 2781 (1969).
Roggero, et al., Bull. De La Societe Chimique De France, 11:4021 (1971). 62-45553.
Allan, et al., Journal of Organic Chemistry, 23:112 (1958).
Fujita, et al., Diabetes, 32:804 (1983).
Sohda, et al., Chem. Pharm. Bull., 30:3563 (1982).
Sohda, et al., Chem. Pharm. Bull., 30:3580 (1982).
Sohda, et al., Chem. Pharm. Bull., 32:2267 (1984).
Tomisawa, et al., Chem. Pharm. Bull., 34:701 (1986).
Isomura, et al., Chem. Pharm. Bull., 32:152 (1984). 62-29570.
Derwent Abstracts, 87-076383/11, abstracting, J6 2029-579A no date.

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