Benzylidene derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142225, 514342, 514372, 514446, 544 2, 544 3, 546280, 548214, 549 78, C03D27502, A61K 3154

Patent

active

054182301

ABSTRACT:
Benzylidene derivatives having anti-inflammatory activities, are shown by the following formula I: ##STR1## wherein A is -CH.sub.2 - or -CH.sub.2 CH.sub.2 -; B is a bond or -CH.sub.2 -, -CHOH-, -CO-, -O-, or A and B may taken together form -CH=CH-; D is >N- or >CH-; R.sup.1 and R.sup.2 each independently is hydrogen, lower alkyl or lower alkoxy; R.sup.3 is hydrogen, lower alkyl, cycloalkyl, lower alkoxy, arylalkyloxy, heteroarylalkyloxy, lower alkylcarbonyl, arylcarbonyl, substituted or unsubstituted carbamoyl, or a group of the formula:

REFERENCES:
patent: 4895862 (1990-01-01), Alessi
Mueller et al., Chemical Abstracts, vol. 117 (1992), p. 736 Abstract No. 131100q.
Speranskii, C.A. 84(1)4761F (1975).

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