Benzylaminoaryl-dihydropyridinelactones and their use in medicam

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514302, 544333, 546116, A61K 3144, C07D491048

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active

049046659

ABSTRACT:
A benzylaminoaryl-dihydropyridinelactone compound of the formula (I) ##STR1## in which R.sup.1 represents hydrogen, halogen, cyano, nitro, C.sub.6 -C.sub.12 -aryl, C.sub.1 -C.sub.8 -alkyl, C.sub.1 -C.sub.8 -alkoxy, C.sub.1 -C.sub.6 -alkylthio, trifluoromethyl, trifluoromethoxy, trifluoromethylthio, difluoromethoxy, di-C.sub.1 -C.sub.5 -alkylamino, C.sub.1 -C.sub.6 -alkoxycarboxyl or C.sub.1 -C.sub.6 -alkylsulphonyl,

REFERENCES:
patent: 4532248 (1985-07-01), Franckowiak et al.
patent: 4804667 (1989-02-01), Goldmann et al.
Wagner and Zook, Synthetic Org. Chem., Wiley & Sons, N.Y.C., pp. 666-667, (1953).
Pharmazie Heute, Band 3, No. 104, 1983, Seiten 139-146; R. Manhold et al.: "Pharmakologische Differenzierung von Calcium-Antagonisten".
Chemical Abstracts, Band 85, No. 7, Aug. 16, 1976, Seite 511, Zusammengassungsnr., 46396s, Columbus, Ohio, U.S.; & JP-A-75 131 972.

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