Benzylalcohol amine derivatives

Details Benzylalcohol amine derivatives Benzylalcohol amine derivatives

1975-10-01

1977-06-28

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603437, 26050111, 26050112, 26050118, 26050119, 260592, 424280, 424316, 424330, C07C 9122

Patent

active

040325750

ABSTRACT:
A compound having the formula: ##STR1## wherein Ring A is monohydroxyphenyl, or a pharmaceutically acceptable acid addition salt thereof is prepared by catalytic hydrogenation of a compound having the formula: ##STR2## wherein A' is monobenzyloxyphenyl, and Y is carbonyl or hydroxymethylene. The compound (I) in which Ring A is 4-hydroxyphenyl or 3-hydroxyphenyl is useful as a cardiotonic agent. On the other hand, the compound (I) in which Ring A is 2-hydroxyphenyl is useful as an anti-diabetic agent.

REFERENCES:
patent: 3255249 (1966-06-01), Howe et al.
patent: 3869474 (1975-03-01), Miura et al.
Klosa, "Journal fur Praktiscke Chemie," vol. 36, pp. 1-4 (1967).
Burger, "Medicinal Chemistry," 2nd Ed., p. 597 (1960).
Thrift, "Jour. Chem. Soc. London," Series C, pp. 288-293 (1967).

Affiliated with

Also associated with

Rating

Benzylalcohol amine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzylalcohol amine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzylalcohol amine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1521320