Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1987-09-30
1989-08-29
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514533, 514535, 514562, 514563, 558413, 558415, 558416, 558417, 560 9, 560 13, 560 18, 560 21, 560 34, 560 45, 560 46, 560 47, 560 48, 562430, 562431, 562432, 562435, 562439, 562453, 562456, 562457, 562426, 564 44, 546261, 546265, 546284, 546286, 546287, 546288, 546289, 546292, 546307, 546308, 546309, 546304, 546329, 549 61, 549 62, 549 63, 549 65, 549 68, A61K 3300, A61K 3306, C07C12722, C07C15709, C07C10100
Patent
active
048617997
ABSTRACT:
A benzoylurea compound having the formula: ##STR1## wherein each of X.sub.1 and X.sub.2 is a hydrogen atom, a halogen atom or a methyl group, provided that X.sub.1 and X.sub.2 are not simultaneously hydrogen atoms, Y is independently a hydrogen atom, a halogen atom, an alkyl group which may be substituted by halogen, a --CO.sub.2 R.sub.1 group wherein R.sub.1 is a hydrogen atom, a cation or an alkyl group, or a --OR.sub.1 group wherein R.sub.1 is as defined above, A.sub.1 is .dbd.N--or ##STR2## wherein Y is as defined above, W is an oxygen atom, a sulfur atom or ##STR3## wherein R.sub.1 is as defined above, k is an integer of from 1 to 3, l is 0 or 1, and Ar is ##STR4## wherein Z is independently a hydrogen atom, a halogen atom, an alkyl group which may be substituted by halogen, an alkoxy group which may be substituted by halogen, a nitro group, a cyano group or a --S(O).sub.n R.sub.2 group wherein R.sub.2 is an alkyl group which may be substituted by halogen and n is 0, 1 or 2, A.sub.2 is --S--, ##STR5## wherein Z is as defined above, or ##STR6## wherein Z is as defined above, and m is an integer of from 1 to 3, or a salt thereof.
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Fujii Yasuhiro
Haga Takahiro
Imai Osamu
Koyanagi Toru
Toki Tadaaki
Ishihara Sangyo Kaisha Ltd.
Lee Mary C.
Richter J.
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