Benzoylecgonine conjugate diagnostic reagents

Details Benzoylecgonine conjugate diagnostic reagents Benzoylecgonine conjugate diagnostic reagents

1997-01-31

1998-09-15

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

435 79, 530359, 530363, 530849, 546125, C07D45110, C07D45112, G01N 3353

Patent

active

058080740

ABSTRACT:
A benzoylecgonine conjugate represented by the following formula: ##STR1## wherein, R is H or CH.sub.3 ; R' is --NH--NH--, --(NH).sub.2 --CO--(CH.sub.2).sub.n --CO--NH--NH--, or related linear chains wherein at least one (CH.sub.2) is replaced with a substituent selected from the group consisting of an ether, an amide, a sulfide, a disulfide, an alkyl, an aryl, an alkoxy, an aryloxy or an alkylhalide; and T is a targeting substance selected from the group consisting of proteins, peptides, antigens, polypeptides, dyes, biotins, enzymes, antibodies, hormones, carbohydrates, polysaccharide supports, and filter paper.

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Chemical Abstracts,vol.124:(No.19),abst.No.252,834k,May 6, 1996.

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