Benzoxazole carboxamides for treating CINV and IBS-D

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S224000

Reexamination Certificate

active

11357494

ABSTRACT:
Compounds of formulae I and II:are disclosed as 5-HT3inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.

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